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At the level of body composition, limited DEXA and CT evidence suggests that GLP-1RAs primarily reduce fat massspecifically visceral fatwhile relatively preserving lean mass (54, 75)
It also remains unclear why the effects were specific for total ghrelin and not for acyl-ghrelin
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Injectable GLP-1 RAs are not meal-dependent, while oral semaglutide must be taken on an empty stomach with a small amount of water
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